Specialty Columns (SFC)

Engineered for unmatched chemical stability, breakthrough selectivity, and transformative performance — CromCarb™ redefines the future of small and large molecule separations.

Overview

CromCarb™ is a family of high-performance chromatography columns based on 100% graphitized carbon media. Unlike traditional silica-based or polymeric packings, these all-carbon stationary phases offer a unique combination of extreme chemical stability and broad analyte affinity, enabling efficient separation of both non-polar and polar compounds

Specialty Columns (SFC) Family

Introducing the CromCarb™ Range — Precision Built, Application Tuned.

CromSil™ PAH

Polycyclic Aromatic Hydrocarbon Column

CromSil™ Furo

Furosine Analysis HPLC Column

CromSil™ Acido

Organic Acids HPLC Column

CromSil™ PolySep

Polymeric Reversed-Phase Column (Wide pH Range)

CromSil™ Glyco

Carbohydrate Analysis HPLC Column

Why Choose Pure Carbon? Unlock New Chromatographic Dimensions.

Chromatography is evolving — and CromCarb™ leads the charge. Unlike traditional silica-based columns, CromCarb™ harnesses the full potential of 100% graphitized carbon to offer:

pH 0–14 compatibility — no restrictions, from strong acids to strong bases.
Temperature resilience up to 200°C — high stability under extreme conditions.
Universal retention — seamlessly retains both hydrophobic and hydrophilic compounds.
Phase-collapse immunity — reliable operation in 100% aqueous mobile phases.
Shape selectivity and isomer resolution — separating where silica fails.

Whether you’re tackling small molecules, peptides, proteins, or charged analytes, CromCarb™ provides unrivaled versatility, durability, and chromatographic precision.

CromCarb™ HPLC Columns Comparison (Select | Bio | Multi | Electro)

Feature	CromCarb™ Select	CromCarb™ Bio	CromCarb™ Multi	CromCarb™ Electro
Core Technology	100% Graphitized Carbon	100% Graphitized Carbon (Bio-Optimized)	Epoxy-Activated Carbon	High Conductivity Carbon
Particle Sizes	5 µm, 10 µm, 40 µm, 75 µm	5 µm, 10 µm	5 µm, 10 µm	5 µm, 10 µm
Surface Area	~200–250 m²/g	~100–150 m²/g	Tunable	Tunable
Pore Size	~200 Å	300 Å / 500 Å / 1000 Å	Tunable (Based on Ligands)	Tunable
pH Stability	0–14	0–14	0–14	0–14
Temperature Stability	Up to 200°C	Up to 200°C	Up to 200°C	Up to 200°C
Pressure Tolerance	≥400 bar	≥400 bar	≥400 bar	≥400 bar
Key Mechanism	Hydrophobic, π-π Retention	Bio-molecule Specific Retention	Multimodal (Hydrophobic + Ionic + Affinity)	Voltage-Controlled Ion Capture/Release
Best Suited For	Small Molecules, Polar/Nonpolar Compounds, Isomers	Peptides, Proteins, Oligonucleotides, ADCs	Charge Variants, Glycoforms, Biologics	DNA/RNA Cleanup, Charged Peptides, Desalting
Unique Advantage	No phase collapse under 100% aqueous	Ion-pairing free peptide mapping	Mixed-mode separation in one run	Electrically modulated retention (no salt needed)
Formats Available	Analytical, Flash, Prep	Analytical, Flash, Prep	Analytical, Flash, Prep	-

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Transform challenges into opportunities.