Phenyl (USP L11)

Phenyl (USP L11) – π-π Interactions for Aromatic Compound Separation

Overview

Phenyl columns utilize π-π interactions for the selective retention of aromatic compounds. These columns offer an alternative to standard alkyl phases, providing enhanced selectivity for polarizable molecules.

Key Properties

  • Separation Mechanism: π-π interactions along with hydrophobic retention.
  • pH Range: pH 2–9, offering flexibility for different mobile phases.
  • Carbon Load (100Å Pore Size): Moderate carbon loading to optimize aromatic selectivity.
  • Endcapping: Fully endcapped to improve peak shape and minimize secondary interactions.

Performance & Benefits

Superior Selectivity for Aromatic Compounds Ideal for phenols, benzene derivatives, and polyaromatics.

Balanced Hydrophobic and π-π Interactions Suitable for complex separations.

Regulatory Compliance Meets USP L11 classification.

Reproducible Performance Reliable batch-to-batch consistency.

Recommended Application Areas

  • Pharmaceuticals Separation of drug metabolites with aromatic rings.
  • Environmental Analysis Detection of polycyclic aromatic hydrocarbons (PAHs).
  • Food & Beverage Analysis of flavoring compounds and preservatives.
ChromScience

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