PFP (USP L43)

PFP (USP L43) – High Selectivity for Halogenated and Polar Compounds

Overview

Pentafluorophenyl (PFP) columns provide unique fluorophilic and polar retention, making them ideal for halogenated compounds, acidic analytes, and polar molecules.

Key Properties

  • Separation Mechanism: Fluorophilic, π-π, and polar retention mechanisms.
  • pH Range: pH 2–9, suitable for acidic and basic compounds.
  • Carbon Load (100Å Pore Size): Optimized for fluorinated and halogenated analytes.
  • Endcapping: Fully endcapped for peak shape optimization.

Performance & Benefits

Selective for Fluorinated & Halogenated Compounds Excellent retention.

Polar Interaction Capabilities Ideal for HILIC and reversed-phase.

Enhanced Resolution Ideal for complex samples with mixed polarity.

USP L43 Compliance Meets pharmacopeial method requirements.

Recommended Application Areas

  • Pharmaceuticals Fluorinated drugs and metabolite profiling.
  • Pesticide Analysis High selectivity for halogenated pesticides.
  • Forensic Toxicology Screening of polar drugs and narcotics.
ChromScience

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