CromSil™ Pro Diol (USP L20)

Diol (USP L20) – Polar Phase for Normal-Phase & HILIC Applications

Overview

CromSil™ Pro Diol columns, containing diol-functionalized silica, are versatile for both normal-phase chromatography and Hydrophilic Interaction Liquid Chromatography (HILIC), effectively separating polar analytes.

Key Properties

Separation Mechanism: Polar interactions (Normal-phase/HILIC)

pH Range: 2–8

Carbon Load (100Å Pore Size): Low to moderate

Endcapping: Fully endcapped

Performance & Benefits

✔ Superior polar analyte retention
✔ Compatible with aqueous-organic mobile phases (HILIC)
✔ Stable and reproducible performance
✔ Meets USP L20 specifications

Recommended Application Areas

  • Polar pharmaceuticals
  • Environmental polar analytes
  • Food industry (sugars, organic acids)
ChromScience

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