CromSil™ Orbit

CromSil™ Orbit HPLC Columns

Dependable Solutions for Pharmacopoeial Methods

The Orbit series offers a selection of HPLC columns aligned with the most referenced phases in US and European Pharmacopoeias. Designed for robustness and reproducibility, these columns are ideal for reliable and cost-effective method development and validation. Each stationary phase is bonded to ultra-pure spherical silica gel with a narrow particle size distribution, ensuring consistent performance across various applications.

Orbit Column Variants:

Orbit C18:

USP Designation: L1
Phase: Octadecyl silane bonded to porous silica
Particle Sizes: 3, 5, and 10 µm
Application: Reversed-phase separations of hydrophobic compounds

Orbit N

USP Designation: L3
Phase: Porous silica particles
Particle Sizes: 3, 5, and 10 µm
Application: HILIC, normal-phase, and weak cation-exchange separations

Orbit C8

USP Designation: L7
Phase: Octylsilane bonded to high-quality silica
Particle Sizes: 3, 5, and 10 µm
Application: Reversed-phase separations based on hydrophobicity

Orbit AP

USP Designation: L8
Phase: Aminopropylsilane bonded to silica gel
Particle Sizes: 3, 5, and 10 µm
Application: Normal-phase and weak anion-exchange separations

Orbit CN

USP Designation: L10
Phase: Cyano groups bonded to silica particles
Particle Sizes: 3, 5, and 10 µm
Application: HILIC or normal-phase separations of polar compounds

Orbit Phenyl

USP Designation: L11
Phase: Phenyl groups bonded to silica
Particle Sizes: 3, 5, and 10 µm
Application: Reversed-phase separations of aromatic and non-aromatic compounds

Orbit C4

USP Designation: L26
Phase: Butyl silane bonded to silica
Particle Sizes: 3, 5, and 10 µm
Application: Reversed-phase separations of highly hydrophobic compounds

Orbit MA

USP Designation: L78
Phase: Silane ligand with both reversed-phase and anion-exchange functionalities
Particle Sizes: 3, 5, and 10 µm
Application: Mixed-mode separations involving reversed-phase, anion-exchange, and cation-exclusion mechanisms

Orbit MC

USP Designation: L85
Phase: Silane ligand with reversed-phase and weak cation-exchange functionalities
Particle Sizes: 3, 5, and 10 µm
Application: Mixed-mode separations of compounds with varying ionic characteristics

Key Features

Pharmacopoeial Compliance: Orbit columns correspond to widely recognized USP designations, facilitating seamless integration into established methods.
Versatile Separation Modes: The series encompasses a range of interaction mechanisms, including reversed-phase, normal-phase, HILIC, and mixed-mode, catering to diverse analytical needs.

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