C1 (TMS) (USP L13)

C1 (TMS) (USP L13) – Minimal Retention for Fast Separations

Overview

C1 (Trimethylsilane) is a short-chain reversed-phase column with minimal hydrophobic retention, making it ideal for fast separations of highly polar and hydrophilic compounds. It is especially useful when reducing retention time is critical.

Key Properties

  • Separation Mechanism: Hydrophobic interactions with very low retention.
  • pH Range: pH 2–8, best suited for neutral and slightly acidic compounds.
  • Carbon Load (100Å Pore Size): Low carbon loading to prevent excessive retention.
  • Endcapping: Fully endcapped for improved peak symmetry.

Performance & Benefits

Minimal Retention for Fast Analysis Ideal for short run times.

Excellent for Highly Polar Compounds Avoids excessive retention.

USP L13 Compliance Suitable for regulated testing environments.

Batch-to-Batch Reproducibility Ensures consistency in high-throughput applications.

Recommended Application Areas

  • Pharmaceuticals Hydrophilic drug compounds and formulations.
  • Food & Beverage Rapid screening of water-soluble compounds.
  • Environmental Analysis Detection of polar contaminants.
ChromScience

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